Following the withdrawal from the Iran nuclear deal, the United States will reimpose sanctions on Iran and is contemplating new penalties. Leaving aside the political consequences of this decision, the reimposed sanctions and new penalties put insurers under immediate compliance pressure to investigate their risks. Another complication might be conflicts between US and European sanctions. For insurers, it will be necessary to consider both their regulatory duties as well as their contractual remedies, be it under sanction clauses or under statutory laws which might entitle them to decline fulfilment of affected policies or to terminate these policies altogether.